Ark Studios' clients include:
- Apple Computer, Inc.
- Art Technology Group
- Aurora & Quanta Productions
- BayBank
- Boston Museum of Science
- Botticelli Interactive, Inc.
- Chicago Museum of Science & Industry
- Heinle & Heinle
- Houghton Mifflin Interactive
- Intermetrics
- Interval Research
- Lexia Learning Systems
- Massachusetts Corporation for Educational Television
- Massachusetts Institute of Technology
- Odyssey Project
- PhenomenArts
- PureSpeech, Inc.
- Powercell Corporation
- ZOOM Telephonics